Clean Cold Rooms and Clean Warm Rooms (Filtered Air Series)
With the HEPA filtered clean cold and clean warm room series product line, Environmental Specialties (ES) can provide an installation meeting the most stringent clean air standards. The clean room series is designed for the cold and warm extremes typically found in today's Bio-pharma operations. Ranges from -20°C to +40°C are typical. Current chamber designs offer the benefits of close tolerance temperature and humidity uniformity as well as assurance of a certified clean room environment by control of airborne particulates and microorganisms. With innovative layouts, these ES environmental chambers can be designed within the confines of modular or "stick built" cleanroom facilities and meet or exceed the cleanliness standards of the adjacent areas.
Applications
- Clean filling operations
- Sterility plate studies
- Cell and tissue culture
- Fermentation
- Media preparation
- Packaging under controlled temperature, humidity and clean room conditions
- General incubation and growth
- Vaccine production
Clean Cold & Warm Room Series - Standard Features
- Clean room design standards from Class 100 to 100,000 available.
- Modular metal skinned panels with urethane insulated tongue and groove construction for chamber enclosure. All interior panel surfaces are a smooth nonshedding painted aluminum, galvanized steel, or stainless steel (recommended).
- "Cam-locking" clean room panel seams sealed with FDA approved sealants for a smooth cleanable surface.
- Internal stainless ceiling plenum housing mounted above lay-in tiles.
- Totally accessible hinged drain pan for maintenance and cleaning of all interior plenum components.
- PSC fan motors for energy efficiency. All fan motors rated for operating temperatures of chamber. Motors are remoted from chamber interior where application exceeds rating.
- Automatic defrosting with refrigerant hot gas and/or electric heat for quick and efficient operation.
- Uniform horizontal and vertical air distribution through ducted terminal lay-in HEPA filters in aluminum housings or complete pressurized plenum ceiling. Support achieved with anodized aluminum T-bar drop ceiling network. All solid "filler" clean room tiles constructed of nonshedding acoustical material.
- Perforated metal diffuser grills to protect terminal filter media.
- Terminal filters provided with adjustable air flow damper and static pressure port.
- Stainless false wall air returns at floor level are provided for ceiling plenums or air handlers. Returns feature gross mesh or pleated filters within "ledge" free channels.
- Sealed utility and sprinkler access penetrations.
- Semi-hermetic continually operating compressors for extended equipment life and maximum chamber temperature control and uniformity.
- Fully accessible control panel to efficiently and securely house all controls, alarms, and recording devices. "Ledge" free designs available.
- Touchscreen system control of chamber parameters.
- Fluorescent clean room style lay-in troffers or tear drop fixtures for chamber illumination.
- Factory leak testing of all refrigeration assemblies prior to shipment.
- Bench testing of complete control panel and electrical devices performed prior to shipment.
- Applicable ISO listing 9001:2000 applies.
Clean Cold & Warm Room Series Options - Structural / Electrical
- Magnehelic / photohelics provided for monitoring prefilter and HEPA pressure drop.
- Lowered classification zones within chamber for critical operations.
- Prefilter and HEPA loading alarms.
- Stainless wall, ceiling and floor finishes.
- Electrical wiring to NEC standards for Cl I
Division I or II environments. - Product security through dead bolts keyed to building. All security locking mechanisms are furnished with internal emergency relief.
- Flush thermopane view window in door or wall panels.
- Access ports and clean room pass throughs.
- Recessed duplex outlets within chamber walls.
- Seamless floor covering over complete chamber area with coving.
- Exterior/ interior door ramps.
- Pressurized anteroom or air showers for personnel entry.
- Emergency personnel lighting for chamber exit.
- Chamber airflow and pressure alarms (high and low).
- Emergency lighting systems.
- RS 232 / 485 or 4-20 mA comms available.
Clean Cold & Warm Room Series Options - Mechanical
- Exhaust fans with stainless steel HEPA filtered air intake and housing.
- Base level dehumidification with a proportional reheat package.
- Extended range dehumidification by ES developed and field proven proportional air volume regenerative desiccant drier. This design allows close tolerance control and extended life of drier components.
- Humidification by independent passivated stainless steel steam generator designed for pure supply water.
- Air returns designed to be integrated into the insulated room wall panels.
- Copper or phenolic coated evaporator fin construction for protection in corrosive environments.
- Point of use water purification systems for steam generator supply water.
- Complete 100% redundant backup refrigeration systems with automatic switchover.
- Remote air handler can be provided to remove all mechanical components from above the suspended clean room tiles and eliminate the disturbance of the ceiling area and room.
- Available designs for temperature uniformity throughout entire chamber to ± 0.5°C.
- Available designs for humidity uniformity throughout entire chamber to ± 3 %RH.
- Conditioning packages designed to use host building chilled water systems for chamber cooling.
- Non-refrigerated cooling using building ventilation available for certain special applications.